Jul. 14th, 2016

rebeccmeister: (1x)
I wanted to get up and go rowing this morning, but I just could not. Instead, after seeing [livejournal.com profile] scrottie off to the train station, I slept for another three hours. That's the carryover cost of staying up until 2 am on Tuesday night/Wednesday morning.

This morning, I learned that they've found yet another tumor on my father's liver via a careful MRI scan. This means that the tumor ablation procedures they've tried previously probably won't really work, and so continued chemotherapy is the current best course of action.

When my friend with the recurrent tongue and throat cancer received her most recent diagnosis (she is on cancer number four at this point), I spent a brief amount of time reading about the immunotherapy methods that are sometimes used to treat cancers such as hers. There were multiple good arguments in favor of pursuing the immunotherapy route for her case, but ultimately her insurance company wouldn't cover any of them anyway and so she's also going through chemotherapy in advance of inevitable and extensive surgery.

For me, the liver is an amazing, but dark and obscure, organ. It doesn't remind us of its existence, most of the time, unlike the beating of our heart, the sighs and wheezes of our lungs, the growling of our stomachs and bowels, the fullness of our bladders, the tightness of a headache. The liver is crucial to our well-being, however, because it is our metabolic centerpoint. It detoxifies toxins and interconverts nutrients, and thus it is an organ that experiences high levels of chemical stress. Vigilant people pay close attention to things that adversely affect the liver, like alcohol, but in general it's easy to ignore or forget about. For instance, my father hasn't experienced any noticeable symptoms from any of the growths on his liver.

Given its central role, there's room for a whole lot to go wrong with the liver. Multiple tumors are likely to reflect multiple different kinds of deleterious mutations, and the only way to really know what's going on would be to biopsy all of the different problematic spots, which sounds tremendously invasive. And then, if different tumors have different things going on, it would be difficult to pick the right combination of immunotherapy drugs to effectively cover all the bases. And at some point, we all die anyway, it's just a matter of the form of bodily failure we experience, and what we do in the meantime.

Meanwhile, here we are.

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