I think there's still some chance of infection with road rash because a large surface area gets exposed. But the appropriate first aid treatment is pretty straightforward: just use something like hydrogen peroxide to kill microbes and clean the wound while the wound is still fresh, keep it clean while it dries out, and let it air and dry out. Scabs are the best band-aids. The only time I use band-aids are when I have a wound in a place that gets submerged in water a bunch (e.g. cuts on my fingers).